The Steelers were able to keep all of their picks except seventh-rounder Doug Worthington, a defensive end who could be called back to the practice squad by the start of next week.
Worthington, or any other player eligible for the practice squad, must first clear league waivers. They then have the option to choose from among interested teams.
The Steelers also have a ninth draft pick, offensive tackle Chris Scott, on the Physically Unable to Perform list for at least the next six weeks.
Suspended quarterback Ben Roethlisberger doesn't count among the roster count.
Those cut Saturday were: LB Patrick Bailey, CB Joe Burnett, S Da'Mon Cromartie-Smith, WR Tyler Grisham, DE Sunny Harris, C Justin Hartwig, KR Stefan Logan, NT Steve McLendon, RB Frank Summers, OG Kraig Urbik, and Worthington.
Logan was the only other role player cut. Last season's kick returner lost his job, most likely, to rookie WR Antonio Brown.
Aside from the three quarterbacks, the Steelers' 53-man roster includes four running backs, three tight ends, six wide receivers, nine offensive linemen, six defensive linemen, nine linebackers, 10 defensive backs, a punter, a long-snapper and a kicker. Included in that group are two legitimate punt gunners, CB Anthony Madison and WR Arnaz Battle.
The Steelers begin preparations Monday for their opener Sept. 12 against the visiting Atlanta Falcons.